BIOGRAPHY
Dr. Sheng-Jia Lin is an Assistant Professor of Biology at Utah Tech University. His research focuses on integrating human genetics, genome editing, vertebrate disease models, and human brain organoid systems to understand the molecular mechanisms underlying neurodevelopmental disorders.
His lab develops and applies advanced model systems, including zebrafish and human brain organoids (three-dimensional cell culture models that mimic human brain structure), to functionally validate patient-derived genetic variants. By combining CRISPR/Cas9 and base editing technologies with transgenic animal models and 3D human cell culture systems, his work bridges genetic discovery and experimental validation.
Through these approaches, Dr. Lin’s research provides mechanistic insights into disrupted brain development and sensory function. His work is further strengthened by international collaborations with clinicians and geneticists, enhancing the translational impact of his research in improving the diagnosis and understanding of neurodevelopmental disorders.