Variant Science Academic Certificate

Department of Biology

Unlock the science behind genetic variation and gain the skills to turn complex genomic data into meaningful clinical insights.

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Shape the Future of Precision Medicine

The field of genomic variant analysis is growing rapidly. As healthcare becomes more personalized and treatments more targeted, professionals who can interpret genetic variants are in high demand across pharmaceutical companies, hospitals, and diagnostic labs.

This certificate gives you the knowledge and skills to step into variant science roles or advance in your current position. Whether you’re transitioning from an adjacent field or you’re already working as a variant scientist who was trained on the job, this program provides the formal education and comprehensive training that many professionals in this field never received.

You’ll learn how to classify genetic variants across multiple disciplines, interpret their clinical significance, and match them to targeted therapies. The program covers both germline and somatic analysis, giving you breadth beyond what most workplace training provides.

As a clinical variant scientist, you’ll collaborate closely with genetic counselors, laboratory directors, pathologists, and ordering clinicians to evaluate genomic findings within their clinical context. Your primary role is to assess the clinical significance of detected variants using established guidelines, curate supporting evidence from the literature and databases, and contribute to high-quality, medically actionable reports. Your analyses support accurate diagnoses, inform management decisions, and guide clinicians toward the most appropriate follow-up testing or therapeutic options for their patients.

Complete the certificate in six months at your own pace. Start when you’re ready.

PROGRAM TYPE

Academic Certificate

DEGREE

Non-credit-bearing Professional Certificate

OFFERED AS

Asynchronous Learning Environment, 100% Online

COLLEGE

Science, Engineering, and Technology

Learn About the Program

Hear from Dr. Howard L. McLeod, FASCO, FCCP, Professor & Center Director, Utah Tech University, and a leading expert in pharmacogenomics, speak about what variant scientists do and why this work matters in modern healthcare.

Watch Video

Why This Certificate

  • Study on your own schedule in a fully online, self-paced format. You have six months to complete the program.
  • This is the first academic certificate created specifically for variant science professionals. The curriculum fills real gaps in current training.
  • Gain the formal, broad-based education that on-the-job learning often does not provide. Expand beyond your current specialty and build cross-disciplinary skills.
  • Train with the same databases, tools, workflows, and classification guidelines used in clinical laboratories.
  • Build competency in both germline and somatic variant analysis, with a strong focus on oncology applications where demand is highest.
  • Prepare for roles in healthcare systems, diagnostic laboratories, pharmaceutical and biotech companies, and regulatory agencies.
  • Program fee is $3,000 with no additional costs.

What You’ll Learn

By the end of this certificate, you’ll be able to:

  1. Understand the foundations of variant science.
    Describe how the field developed and how variant interpretation is applied in clinical care, pharmaceutical research, and legal contexts. Explain how genetic variants contribute to disease at the molecular and cellular level.
  2. Evaluate and interpret genetic variants.
    Distinguish major variant types, assess their impact on gene and protein function, and classify germline and somatic variants using established guidelines and supporting evidence.
  3. Use the tools and workflows of a clinical variant scientist. 
    Work with the core databases, software platforms, and laboratory technologies used in clinical genomic analysis. Integrate phenotype, family history, and current literature to determine clinical relevance.
  4. Translate genomic findings into clinical action.
    Connect variants to potential targeted therapies or management options and communicate complex results clearly to clinicians, genetic counselors, and other members of the care team.

Program fee: $3,000

No application fee and no hidden costs. A focused investment in a high-impact skillset. Financial aid is not available.

100% online

Complete the entire certificate from home on your own schedule. Full flexibility without compromising academic rigor.

Curriculum

The certificate has ten modules that you complete on your own over six months. The modules follow a sequence, starting with genetics basics and building toward advanced variant analysis and clinical applications.

Each module includes focused lessons, hands-on exercises, and assessments. You'll need to finish all ten modules within the six-month window to earn your certificate.

Module 1: Welcome and Orientation

Get familiar with the learning platform, program expectations, and what you need to do to succeed.

Module 2: Fundamentals of Genetics

Review molecular genetics essentials like gene structure, DNA replication, transcription, and translation. These basics are the foundation for everything else.

Module 3: Mechanisms of Genetic Diseases

Learn how genetic variants lead to disease. You’ll study different pathogenic mechanisms including loss of function, gain of function, and dominant negative effects.

Module 4: Introduction to Genetic Variant Analysis

Understand where variant science came from and how it’s applied in healthcare and legal settings today. See how variant scientists fit into clinical and research teams.

Module 5: Germline Variant Classification, Part 1

Start working with ACMG/AMP guidelines for classifying germline variants. Learn to evaluate population frequency data, computational predictions, and functional evidence.

Module 6: Germline Variant Classification, Part 2

Go deeper into germline classification. Cover segregation analysis, de novo variants, and complex inheritance patterns. Practice with real clinical cases.

Module 7: Oncology and Somatic Variant Classification, Part 1

Switch to somatic variant analysis with a focus on cancer. Learn about tumor biology, cancer genomics, and how somatic classification differs from germline.

Module 8: Oncology and Somatic Variant Classification, Part 2

Apply AMP/ASCO/CAP guidelines for interpreting somatic variants. Learn to spot actionable mutations and connect them to targeted therapies and clinical trials.

Module 9: Complex Variant Analysis

Work through challenging cases involving structural variations, copy number variants, and variants of uncertain significance. Build strategies for solving tough problems.

Module 10: Regulatory Approvals, Clinical Trials, and Pharmacology

Learn the regulatory side of genetic testing and precision medicine. Understand FDA approval processes, clinical trial design, and how pharmacogenomics works.

Who Should Apply

This certificate is ideal for professionals in:

  • Variant science and genomic analysis
  • Genetic counseling and precision medicine services
  • Clinical diagnostic laboratories
  • Pharmaceutical and biotech research
  • Healthcare and hospital-based genomics teams
  • Regulatory and quality oversight roles
  • Academic or industry research programs
  • It supports working variant scientists seeking formal, comprehensive training and serves biology-trained professionals preparing to move into clinical genomics, genetic testing, or roles involving variant interpretation.

Application Requirements & Information

You need a bachelor’s, master’s, or doctoral degree in biological sciences or a related field. Send transcripts with your application.

You also need professional experience in a healthcare, diagnostic lab, or pharmaceutical setting. This could be work as a variant analyst, genetic counselor, bioinformatician, research scientist, computational biologist, or a similar role adjacent to clinical variant science.

Your CV should show the admissions committee what experiences and skills make you a strong candidate for the Variant Science Academic Certificate.

Write a statement explaining why you want to pursue this certificate. Talk about the skills you already have that prepare you for this program. Tell us what excites you about this field.

 

  • Complete the online application through Utah Tech University’s Graduate Admissions portal. Include your transcripts, CV, and statement of purpose.
  • The program director reviews your materials.
  • If you’re accepted, you’ll get enrollment instructions and a checklist.
  • Complete the enrollment checklist. This includes acknowledging the program handbook, AI policy, and student expectations. Then submit your payment.
  • Access your course materials and begin your six-month program.

We accept applications year-round and review them as they come in. Apply when you’re ready. Once accepted, you can start the program on your schedule.

What You’ll Gain

  • You’ll complete the program with strengthened variant interpretation skills and a portfolio of applied case analyses aligned with current clinical practices.
  • Proficiency using the databases, tools, and guidelines essential for clinical variant analysis
  • Deeper understanding of germline and somatic variant classification, evidence evaluation, and report development

Hands-on Experience

  • You will practice interpreting real-world genomic findings and applying established frameworks to clinical scenarios.
  • Curating literature, functional data, and population evidence
  • Classifying variants using guideline-driven approaches (ACMG/AMP and related frameworks)
  • Integrating phenotype and family history into clinical significance assessments

Frequently Asked Questions

What if I don't have experience working directly as a variant scientist?

That’s exactly who this program is for. We’re looking for people with adjacent experience in roles like genetic counseling, bioinformatics, research science, or laboratory work in healthcare or pharmaceutical settings. If you’ve worked with genetic data or in clinical labs, even in supporting roles, you likely have relevant experience.

I'm already working as a variant scientist. Will this program help me?

Yes. Most clinical variant scientists learn on the job and specialize in one area based on their employer’s focus. If you work in pharma, you might focus on somatic variants and drug development. In a diagnostic lab, you might specialize in germline analysis. In healthcare, your focus might be clinical interpretation. This program gives you comprehensive training across all these areas, so you can broaden your expertise or move into different sectors. You’ll also earn professional certification that formalizes the knowledge you’ve built through experience.

How much time should I expect to spend on coursework each week?

Because the program is self-paced, this varies by person. Most students spend 8-12 hours per week on coursework, but you can adjust based on your schedule. The key is completing all ten modules within the six-month deadline.

Do I need to complete modules in order, or can I jump around?

Modules are designed to be completed in sequence. Each module builds on concepts from previous ones, so you’ll need to work through them in order. This ensures you have the foundational knowledge before tackling more advanced topics.

What happens if I can't finish within six months?

The six-month deadline is firm to keep the program focused and ensure timely completion. If you think you might need more time, consider whether this is the right moment to start the program. We want you to succeed, and that means being realistic about your available time.

Will I have access to instructors or support during the program?

Yes. While the program is self-paced and asynchronous, you’ll have access to program support throughout your six months. This includes technical support for the learning platform and guidance from program staff when you have questions about course content.

Can I work full-time while completing this certificate?

Yes. The program is designed for working professionals. The asynchronous, self-paced format means you can fit coursework around your job. Many students complete modules in evenings and weekends.

What technology or software do I need?

You’ll need a computer with reliable internet access. The program uses standard web browsers for accessing course materials. You’ll work with industry-standard databases and tools during the program, but these are provided through the learning platform. Specific technical requirements will be shared upon acceptance.

Contact

Todd Purcell

Program Director

Email: todd.purcell@utahtech.edu

Phone: 435.652.7732

Jamie Garner

CSET Graduate Admissions Coordinator

Email: jamie.garner@utahtech.edu

Phone: 435.879.4266

Office: HCCLIB 458a

Office of Graduate Studies

Email: GraduateStudies@utahtech.edu

Schedule Appointment