Biography
Dr. Ayyappa Sista Kameshwar is an Assistant Professor of Bioinformatics in the Department of Biology at Utah Tech University.
He earned a bachelor’s degree in biotechnology from Osmania University, a master’s degree in biotechnology from VIT University,
and a Ph.D. in biotechnology from Lakehead University. Prior to joining Utah Tech, he completed postdoctoral research
appointments at Texas A&M University, the University of Calgary, and the University of Guelph, and brings industry
experience from Strand Life Sciences and SCIEX (Danaher Corporation). His research focuses on biotechnology, genomics, and
bioinformatics, with an emphasis on data-driven biological analysis and translational research.
Previous Teaching
Dr. Kameshwar began his teaching career as a teaching and research assistant at Lakehead University. During his doctoral and
postdoctoral training at Lakehead University and the University of Guelph, he taught genetics, biochemistry, microbiology,
bioinformatics, plant biology, and molecular biology at the undergraduate, graduate, and doctoral levels. As a postdoctoral
research associate and fellow at Texas A&M University, the University of Calgary, and the University of Guelph, he delivered
advanced courses and workshops in bioinformatics, R programming, and next-generation sequencing data analysis, combining strong
theoretical foundations with hands-on computational training.
Experience
- Nine years of teaching experience
Research & Interests
- Computational biology
- Multi-omics integration
- Comparative genomics
- Evolutionary developmental biology
- Model organism systems (zebrafish, mouse, human)
- Single-cell and spatial transcriptomics
- Chromatin accessibility and epigenomics
- Gene regulatory networks
- Pediatric disease mechanisms
- Bioinformatics tool development
- Public genomic data mining
- Machine learning in genomics
- Systems biology
- Translational medicine
Publications & Projects
-
Cwiek, A., Dailey, R.K., Sista Kameshwar, A.K., et al. (2025).
Preterm birth increases susceptibility to hyperglycemia-induced glomerular alterations in male mice.
Scientific Reports, 15(1). -
Hao, X., Sista Kameshwar, A.K., Chio, C., et al. (2024).
Elucidating downstream pathways triggered by H₂S signaling in Arabidopsis thaliana under drought stress via transcriptome analysis.
Plant Signaling & Behavior, 19(1). -
Zhang, X., Li, C., Chio, C., Sista Kameshwar, A.K., et al. (2020).
Transcriptome analysis identifying genes involved in lignan, sesquiterpenoid, and triterpenoid biosynthesis in Kadsura heteroclita.
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 48(4), 1802. -
Wu, Y., Sista Kameshwar, A.K., Zhang, B., et al. (2022).
Genome and transcriptome analysis of rock-dissolving Pseudomonas sp. NLX-4 strain.
Bioresources and Bioprocessing. -
Chen, F., Ye, J., Sista Kameshwar, A.K., et al. (2019).
A novel cold-adaptive endo-1,4-β-glucanase from Burkholderia pyrrocinia JK-SH007.
Frontiers in Microbiology, 10, 3137. -
Sista Kameshwar, A.K., Ramos, L.P., Qin, W. (2019).
CAZymes-based ranking of fungi (CBRF): An interactive web database for identifying fungi with plant biomass-degrading abilities.
Bioresources and Bioprocessing, 6(1). -
Sista Kameshwar, A.K., Qin, W. (2019).
Systematic metadata analysis of brown rot fungi gene expression data reveals genes involved in Fenton’s reaction and wood decay.
Mycology. -
Chen, X., Sista Kameshwar, A.K., Chio, C., et al. (2019).
Effect of KNO₃ on lipid synthesis and CaCO₃ accumulation in Pleurochrysis dentata coccoliths.
International Journal of Biological Sciences, 15(13), 2844–2858. -
Sista Kameshwar, A.K., Qin, W. (2018).
Molecular networks of Postia placenta involved in lignocellulosic biomass degradation.
International Journal of Biological Sciences, 14(3), 237–252. -
Sista Kameshwar, A.K., Qin, W. (2018).
Analyzing gene expression patterns controlling lignocellulose-degrading enzymes in Phanerochaete chrysosporium.
Process Biochemistry, 64, 51–62. -
Sista Kameshwar, A.K., Qin, W. (2017).
Comparative genome-wide analysis of CAZymes in white rot, brown rot, and soft rot fungi.
Mycology. -
Sista Kameshwar, A.K., Barber, R., Qin, W. (2017).
Comparative modeling and molecular docking of fungal laccases using lignin model compounds.
Journal of Molecular Graphics and Modelling, 79, 15–26. -
Sista Kameshwar, A.K., Qin, W. (2017).
Gene expression metadata analysis of lignin degradation and detoxification mechanisms.
Current Genetics. -
Sista Kameshwar, A.K., Qin, W. (2017).
Metadata analysis identifies common CAZyme profiles involved in cellulose and hemicellulose degradation.
International Journal of Biological Sciences, 13(1), 85–99.
Conferences & Workshops
- Texas Genomic Society Meeting (2024, 2025)
Awards & Honors
- Student Research Innovation Award of the Year, Lakehead University (2018, 2019)
- Mitacs Globalink Fellowship (2018)
- Ontario Trillium Scholarship (2015–2019)